Agenda | ADDS 2025

Kick OffFebruary 10
Day 1February 11
Day 2February 12

1:00 PM → 1:30 PM

ALS Pre-Conference Workshop

1:00 PM → 1:30 PM

Pathway to regulatory-accepted Digital Endpoint: Lessons Learned from Case Studies

Coral Reef Room

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

1:30 PM → 1:50 PM

What is the Endgame? Multistakeholder Perspectives for Clinicians, Industry, Regulators and Patients

Coral Reef Room

Dr. Nadia Sethi

Co-Chair and Advocacy Committee
Northeast ALS Consortium Patient Education

1:50 PM → 2:50 PM

Current Level of Evidence

Roundtable Presentation

Coral Reef Room

This roundtable session will focus on how we can accelerate the integration of actigraphy in ALS research. This session brings together experts to discuss the current level of evidence that exists for digital endpoints in ALS. Panelists will then discuss what near-term next steps are necessary to generate the evidence needed to validate these digital endpoints for use in clinical research and development. Participants will have the opportunity to engage in meaningful dialogue and contribute to shaping the future of ALS research.

Ruben van Eijk, MD

UMC Utrecht

Fernando Vieira, MD

ALS Therapy Development Institute

Cheryl Coon, PhD

Critical Path Institute

Frederik Steyn, PhD

University of Queensland

2:50 PM → 3:00 PM

Break

Coral Reef Room

3:00 PM → 5:00 PM

Interactive Discussion

Coral Reef Room

Gap Mapping: What we need to know?
Evidence Generation: How do we get there in the next 3-5 years?
Concluding discussion and formulation of action plan

6:00 PM → 8:00 PM

Welcome Reception

Emerald Coast Room

Please join us for the official ActiGraph Digital Data Summit 2025 kick off with refreshments and hors d'oeuvres. Early event check-in will be available till 8:00 PM.

7:30 AM

Registration Opens

Ballroom Foyer 1-2

7:30 AM → 8:30 AM

Breakfast

Ballroom Foyer 1-2

8:30 AM → 9:00 AM

Welcome and Opening Remarks

Ballroom A-F

Jeremy Wyatt

Chief Executive Officer
ActiGraph

9:00 AM → 5:00 PM

Physical Activity Focused Sessions

9:00 AM → 9:30 AM

The Pfizer Journey to Novel Digital Measures

Keynote Presentation

Ballroom A-F

Tim McCarthy, PhD

VP and Head of Biomeasures, Endpoints and Study Technologies
Pfizer

9:30 AM → 9:45 AM

What Actigraphy Can Tell us in Pulmonary Arterial Hypertension

Featured Speaker

Ballroom A-F

Daniel Lachant, DO

Assistant Professor of Medicine
University of Rochester Medical Center

9:45 AM → 10:00 AM

Title TBD

Featured Speaker

Ballroom A-F

Daniel Sanchez

Associate Director, Oncology Data Science and Digital HealthResearch and Development
J&J Innovative Medicine

10:00 AM → 10:30 AM

Networking Break / Sponsor Exhibits

Ballroom Foyer 1-2

10:30 AM → 10:45 AM

Developing a Novel Digital Endpoint for Cancer Cachexia

Featured Speaker

Ballroom A-F

Lukas Adamowicz

Senior Data Scientist
Pfizer

10:45 AM → 11:05 AM

ActiGraph Science and Technology Roadmap

Featured Speakers

Ballroom A-F

Kim Rejndrup

Chief Product Officer
ActiGraph

Ali Neishabouri, PhD

Head of Data Science
ActiGraph

11:05 AM → 11:35 AM

Lessons Learned

Panel Discussion

Ballroom A-F

11:35 AM → 1:00 PM

Lunch

White Sands Room

1:00 PM → 4:45 PM

ALS Mini-Symposium

1:00 PM → 1:15 PM

Use and Limitations of Current Clinical Outcome Assessments in ALS

Ballroom A-F

1:15 PM → 1:30 PM

DigitALS Working Group: Systematic Review and Best Practice

Featured Speaker

Ballroom A-F

Emma Hodson-Tole, PhD

Professor of Neuromuscular Biomechanics
Manchester Metropolitan University

1:30 PM → 2:00 PM

ALS TDI Takeaway in Large-Scale Actigraphy Research

Keynote Presentation

Ballroom A-F

Fernando Vieira, MD

CEO and Chief Scientific Officer
ALS Therapy Development Institute

2:00 PM → 2:30 PM

Selected Talks

Ballroom A-F

2:30 PM → 3:30 PM

Scientific Poster Session / Networking Break

Ballroom Foyer 1-2

3:30 PM → 3:45 PM

Patient-Centered Research for ALS Endpoint Development

Featured Speaker

Ballroom A-F

Cheryl Coon, PhD

Vice President, Clinical Outcome Assessment (COA) Program
Critical Path Institute (C-Path)

3:45 PM → 4:30 PM

ALS Pre-Conference Workshop Readout

Panel Discussion

Ballroom A-F

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

4:30 PM → 4:45 PM

Day 1 Wrap Up

Ballroom A-F

Jeremy Wyatt

Chief Executive Officer
ActiGraph

7:00 PM → 9:00 PM

Evening Reception with Cocktails & Tapas

Ballroom A-F

7:30 AM

Registration Opens

Ballroom Foyer 1-2

8:00 AM → 9:00 AM

Breakfast

Ballroom Foyer 1-2

9:00 AM → 9:30 AM

Regulatory Guidance on the Development of Novel Digital Endpoints

Keynote Presentation

Ballroom A-F

Michelle Campbell, PhD*

Associate Director, Stakeholder Engagement and Clinical Outcomes, Office of Neuroscience
FDA

*Pending confirmation

9:00 AM → 12:15 PM

Cohort Studies Session

9:30 AM → 9:45 AM

NHATS: Considerations for Implementation in Large Cohort Studies

Featured Speaker

Ballroom A-F

Jennifer Schrack, PhD

Professor and Director, Center on Aging and Health
The Johns Hopkins University

9:45 AM → 10:00 AM

Digital Health Data in Surveillance: NHANES 2027

Featured Speaker

Ballroom A-F

Dana Wolff-Hughes, PhD

Program Officer
National Cancer Institute

10:00 AM → 10:15 AM

UK Biobank

Ballroom A-F

Laura Brocklebank, PhD

University of Oxford

10:15 AM → 10:45 AM

Networking Break / Sponsor Exhibits

Ballroom Foyer 1-2

10:45 AM → 12:45 PM

Multi-Stakeholder Collaboration Session

10:45 AM → 11:15 AM

Stepping into the Real World with Mobilise-D

Keynote Presentation

Ballroom A-F

Brian Caulfield, PhD

Professor of Physiology, PI and Founding Director, INSIGHT Centre for Data Analytics
University College Dublin

11:15 AM → 12:00 PM

Digital Endpoint Collaboration to accelerate Outcome DEvelopment (DECODE)

Ballroom A-F

Sylvain Zorman, PhD

Director Digital Health Sciences
ActiGraph

12:00 PM → 12:15 PM

Development of Wearable-Derived Digital Endpoint for Neuromuscular Diseases

Featured Speakers

Ballroom A-F

Tina Duong PT, PhD

Physical Therapist, Sr. Research Scientist, Director or Clinical Outcomes Research and Development
Stanford UniversityDivision of Neuromuscular Medicine

Rakesh Pilkar, PhD

Senior Data Scientist
ActiGraph

12:15 PM → 12:35 PM

Validation of PPG Technology for Vital Sign Monitoring

Featured Speakers

Ballroom A-F

Mathieu Lemay, PhD

Signal Processing and AI Group
CSEM

Matthew Patterson, PhD

Senior Data Scientist
ActiGraph

12:35 PM → 12:45 PM

Closing Remarks

Ballroom A-F

Christine Guo, PhD

Chief Scientific Officer
ActiGraph

2:30 PM → 4:30 PM

Excursion - Trolley to ActiGraph Headquarters Tour

ActiGraph Headquarter

Meet in hotel lobby to board trolley

February 26, 2024 Day 1

Emerald Coast Room

February 27, 2024 Day 2

Ballroom Foyer 1-2

Ballroom A-F